The major symptom of Weil's disease is fever.

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The major symptom of Weil's disease is fever.

Fever is the most consistent early sign of leptospirosis, including its severe form known as Weil’s disease. The body's response to the invading spirochete typically drives a high fever that appears early in the course. While jaundice is a characteristic feature of Weil’s disease due to hepatic involvement, it does not occur in all cases and often develops later as liver injury progresses. Because fever is common to most patients and appears early, it stands out as the major symptom. Rash or abdominal pain can occur but are not defining or as universally present, so they’re less representative of the condition’s typical presentation.

Fever is the most consistent early sign of leptospirosis, including its severe form known as Weil’s disease. The body's response to the invading spirochete typically drives a high fever that appears early in the course. While jaundice is a characteristic feature of Weil’s disease due to hepatic involvement, it does not occur in all cases and often develops later as liver injury progresses. Because fever is common to most patients and appears early, it stands out as the major symptom. Rash or abdominal pain can occur but are not defining or as universally present, so they’re less representative of the condition’s typical presentation.

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